John S. Yu, MD

Vice Chair, Neurosurgical Oncology in the Department of Neurosurgery

Director, Surgical Neuro-Oncology

Professor, Neurosurgery

John S. Yu, MD

Neurosurgery - Pavilion
127 S San Vicente Blvd #A6600
Los AngelesCA





John S. Yu, MD

Vice Chair, Neurosurgical Oncology in the Department of Neurosurgery

Director, Surgical Neuro-Oncology

Professor, Neurosurgery

  • Neurosurgery
  • Brain Tumor

Acoustic Neuromas


Brain Cancer Vaccine

Brain Cancers (Glioma)

Brain Cysts

Brain Lesions

Brain Tumors


Frontal Lobe Tumors

Glioblastoma Multiforme





Spine Tumors (Cervical, Thoracic, Lumbar, Sacral)

Stereotactic Radiosurgery

Trigeminal Neuralgia

The research of John S. Yu, MD, focuses on immune and stem cell therapy for brain tumors, cancer stem cells and their microenvironment in brain tumors. Dr. Yu also researches cancer stem cell-specific cytotoxic T lymphocytes, cancer stem cell signaling, mechanism of cancer invasion, cancer stem cell-specific cytotoxic T lymphocytes, targeted immunochemotherapy using nanotechnology, and development of imaging and diagnostic agents using nanoparticles.

  • Undergraduate: Stanford University, 1985
  • Fellowship: National Institute of Mental Health, 1989
  • Master's: Harvard-MIT Division of Health Sciences and Technology, 1990
  • Medical School: Harvard Medical School, 1990
  • Residency: Massachusetts General Hospital, 1997

View CV as a PDF

  • Southern California Super Doctors, Los Angeles Magazine, 2007-present
  • America's Top Cancer Specialists, Newsweek, 2007-present
  • America'a Top Doctors, Castle and Connolly, 2005-present
  • Mahaley Clinical Research Award, American Association of Neurological Surgeons and Congress of Neurological Surgeons
  • Academy Award, American Academy of Neurological Surgery

Click here for a list of peer-reviewed publications.

  • Phuphanich S, Wheeler CJ, Rudnick JD, Mazer M, Wang HQ, Nuno MA, Richardson JE, Fan X, Ji J, Chu RM, Bender JM, Hawkins ES, Patil CG, Black KL, Yu JS. Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma. Cancer Immunol Immunother. 2013;62(1):125-135.
  • Lee BS, Amano T, Wang HQ, Pantoja JL, Yoon CW, Hanson CJ, Amatya R, Yen A, Black KL, Yu JS. Reactive oxygen species responsive nanoprodrug to treat intracranial glioblastoma. ACS Nano. 2013;7(4):3061-3077.
  • Ji J, Judkowski VA, Liu G, Wang H, Bunying A, Li Z, Xu M, Bender J, Pinilla C, Yu JS. Identification of novel HLA-A*0201-restricted, cytotoxic T lymphocyte epitopes on CD133 for cancer stem cell immunotherapy. Stem Cells Transl Med. 2014;3(3):356-364.

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