COVID-19 (Coronavirus)

Christian Stehlik, PhD, MS

Director, Pathology Research

Christian Stehlik, PhD, MS

Phone:

424-315-2670

Christian Stehlik, PhD, MS

Director, Pathology Research

The major research direction in the Stehlik and Dorfleutner Laboratories is elucidating the mechanisms by which innate immune cells sense danger situations, such as tissue injury and infection by pathogens to initiate pathogen clearance, wound healing and tissue repair. Specifically, the lab studies molecular mechanisms of innate immune regulation, primarily investigating cytosolic pattern recognition receptor signaling in inflammasome assembly and type I interferon production in phagocytic cells, such as monocytes, macrophages and Dendritic cells. Inflammation is a central component of these responses and acute and well controlled inflammatory reactions are highly beneficial, while chronic and inappropriate inflammation is linked to tissue destruction and all major inflammatory and immune diseases. Therefore, an important goal of our studies is to define strategies to limit these excessive and uncontrolled inflammatory responses to provide novel avenues for therapeutic intervention.

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  • Master's: University of Vienna, 1994
  • Doctorate: University of Vienna, 1999

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English

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