The laboratory of Ueli Rutishauser, PhD, is investigating the neural mechanisms of learning, memory, and decision making. We are a systems neuroscience laboratory and use a combination of in-vivo single-unit electrophysiology in humans, intracranial electrocorticography, eye tracking, behavior, and computational approaches. An overarching goal is to capitalize on special neurosurgical situations to advance knowledge of the human nervous system. We have helped pioneer the technique of human single-neuron recordings and continue to advance the tools, methods and surgical techniques that allow such experiments. Recent work has focused on the neural mechanisms of episodic memory and single-trial learning, the representation of novelty and familiarity in the human hippocampus, amygdala and basal ganglia, the theta rhythm, the mechanisms of metacognition such as error monitoring, and the neural representation of faces and emotions.

• Doctorate: California Institute of Technology, 2008
• Post Doctorate: California Institute of Technology, 2010
• Post Doctorate: Max Planck Institute for Brain Research, 2012

• Department of Neurology and Neurosurgery
• Epilepsy
• Neurosurgery

• Elected Member, Memory Disorders Research Society, 2018
• Prize for Research in Scientific Medicine, 2017
• Faculty Early Career Development Program CAREER Award, National Science Foundation, 2016
• Biobehavioral Research Awards for Innovative New Scientists (BRAINS) Award, National Institute of Mental Health, 2016
• Next Generation Leader, Allen Institute for Brain Science, 2014

Click here for a list of peer-reviewed publications.

• Minxha J., Adolphs R., Fusi S., Mamelak A.N., Rutishauser U. Flexible recruitment of memory-based choice representations by the human medial frontal cortex. Science, Vol. 368, Issue 6498 (2020)
• Kaminski J, Brzezicka A, Mamelak AN, Rutishauser U. Combined phase-rate coding by persistently active neurons as a mechanism for maintaining multiple items in working memory in humans. Neuron 106(2):256-264 (2020)
• Fu Z, Wu DJ, Ross I, Chung JM, Mamelak AN, Adolphs R, Rutishauser U. Single-Neuron Correlates of Error Monitoring and Post-Error Adjustments in Human Medial Frontal Cortex. Neuron. 2019 Jan 2;101(1):165-177.