• Ob/Gyn-Reproductive Endocrinology
• Obstetrics & Gynecology

The research laboratory of Margareta D. Pisarska, MD, investigates the role of differences in the genetics and epigenetics of pregnancies conceived from couples with infertility, including those conceived through in vitro fertilization. The Pisarska lab also investigates the role of alterations in implantation and their role on adverse pregnancy outcomes. Lab members look at how transcriptional regulation is affected by genetics and epigenetics during early implantation in ongoing pregnancies in order to better understand how these changes lead to adverse pregnancy outcomes. Another area of investigation in the laboratory involves transcriptional regulation in the ovary. The lab is looking at how certain transcription factors regulate follicle/egg development and premature loss leading to subsequent infertility. Specifically, the Pisarska lab is investigating the role of FOXL2, a transcription factor associated with premature ovarian failure.

• Medical School: State University of New York Upstate Medical University, 1992
• Residency: Lenox Hill Hospital, 1996

• Fertility and Reproductive Medicine Center
• Obstetrics and Gynecology
• Endometriosis

• Patient Education Committee, American Society for Reproductive Medicine, 2012-present
• Chairperson, Patient Education Committee, American Society for Reproductive Medicine, 2012-present
• Division Member, American Board of Obstetrics and Gynecology, Reproductive Endocrinology and Infertility Division, 2011-16
• Southern California Super Doctors, 2011-14
• Reviewer: Integrative and Clinical Endocrinology and Reproduction Study Section, National Institute of Health, 2009-12

• Jackson S, Hong C, Wang ET, Alexander C, Gregory KD, Pisarska MD. Pregnancy outcomes in very advanced maternal age pregnancies: the impact of assisted reproductive technology. Fertil Steril. 2015 Jan;103(1):76-80.
• Conway D, Patel S, Liem J, Fan K, Jalian J, Williams III J, Pisarska MD. The Risk of Cytogenetic Abnormalities in the Late First Trimester in Pregnancies Conceived Through Assisted Reproduction Fertil Steril 2011. Feb; 95 (2) 503-506.
• Kuo FT, Fan K, Bentsi-Barnes I, Barlow GM, Pisarska MD. Mouse Forkhead L2 (FOXL2) maintains repression of FSH-dependent genes in the granulosa cell. Reproduction 2012 Oct;144(4):485-494.