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Gadi Pelled, PhD

Assistant Professor, Surgery

Gadi Pelled, PhD

Phone:

310-423-8070

Gadi Pelled, PhD

Assistant Professor, Surgery

Novel therapeutic platforms based on biological therapies are required to overcome extensive skeletal tissue loss or degeneration and replace the currently used synthetic prostheses. Complex clinical challenges such as intervertebral disc degeneration, osteoporotic vertebral fractures, tendon and ligament injuries, nonunion fractures and osteoarthritis pose a great challenge to health systems and to clinicians. Gadi Pelled, PhD, has been investigating the use of adult mesenchymal stem cells (MSCs) for skeletal tissue regeneration. His studies have shown that MSCs were able to regenerate skeletal tissues such as bone and tendon. Moreover, Pelled has shown, using state-of-the-art nanotechnological tools, that engineered bone generated by MSCs has chemical, topographical and nanomechanical properties similar to those of natural mature bone. State-of-the-art technologies are needed to promote tissue regeneration and monitor the effect of stem cell implantation. Pelled has used dynamic culture systems in his studies to investigate the feasibility of growing bone tissue in the lab. In addition, he has developed a novel imaging-based method to analyze tissue mechanics in vivo.

View NIH Biographical Sketch

  • Undergraduate: Hebrew University of Jerusalem, 1992
  • Medical School: Hebrew University of Jerusalem, 1995
  • Doctorate: Hebrew University of Jerusalem, 2007
  • Biomedical Sciences
  • Surgery
  • Biomedical Imaging Research Institute
  • Regenerative Medicine Institute (Board of Governors Regenerative Medicine Institute)

English

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