COVID-19 (Coronavirus)

Peter A. Jorth, PhD

Assistant Professor, Pathology and Laboratory Medicine

Assistant Professor, Medicine

Assistant Professor, Biomedical Sciences

Peter A. Jorth, PhD

Phone:

310-967-2712

Peter A. Jorth, PhD

Assistant Professor, Pathology and Laboratory Medicine

Assistant Professor, Medicine

Assistant Professor, Biomedical Sciences

The research interest of Peter Jorth, PhD, is in understanding how microbes evolve during chronic infections to resist therapeutic treatment and the immune system. Pseudomonas aeruginosa causes life-long chronic infections in people with cystic fibrosis. His investigations have shown that P. aeruginosa diversifies during these infections into genetically complex populations that can include antibiotic resistant and susceptible bacterial siblings. These mixed populations likely contribute to treatment failure. He is using the latest genomic and imaging tools to better understand how mutant bacteria evolve during these infections with the goal of ultimately identifying novel targets and developing new treatments to combat antibiotic resistant bacteria.

View NIH Biographical Sketch as a PDF

  • Undergraduate: Kalamazoo College, 2006
  • Doctorate: University of Texas at Austin, 2013
  • Post Doctorate: University of Washington School of Medicine, 2016
  • Post Doctorate: California Institute of Technology, 2018

View CV as a PDF

  • K22 Career Transition Award, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 2018-20
  • Postdoc-to-Faculty Transition Award, Cystic Fibrosis Foundation, 2017-21
  • Postdoctoral Fellowship, Cystic Fibrosis Foundation, 2014-17
  • Graduate Dean’s Prestigious Fellowship Supplement, University of Texas at Austin, 2013
  • Ruth L. Kirschstein National Research Service Award, National Institute of Dental and Craniofacial Research, National Institutes of Health, 2011-14

Click here for a list of peer-reviewed publications.

  • Jorth P, McLean K, Ratjen A, Secor PR, Bautista GE, Ravishankar S, Rezayat A, Garudathri J, Harrison JJ, Harwood RA, et al. Evolved Aztreonam Resistance Is Multifactorial and Can Produce Hypervirulence in Pseudomonas aeruginosa. MBio. 2017 Oct 31;8(5).
  • Jorth P, Staudinger BJ, Wu X, Hisert KB, Hayden H, Garudathri J, Harding CL, Radey MC, Rezayat A, Bautista G, et al. Regional Isolation Drives Bacterial Diversification within Cystic Fibrosis Lungs. Cell Host Microbe. 2015 Sep 9;18(3):307-19. doi: 10.1016/j.chom.2015.07.006. Epub 2015 Aug 20.
  • Jorth P, Turner KH, Gumus P, Nizam N, Buduneli N, Whiteley M. Metatranscriptomics of the human oral microbiome during health and disease. MBio. 2014 Apr 1;5(2):e01012-14.

English

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