COVID-19 (Coronavirus)

Leigh Ellis, PhD

Director, Urologic Oncology Disease Research Group

Associate Professor, Medicine

Leigh Ellis, PhD

8700 Beverly Blvd
Los AngelesCA
90048

Leigh Ellis, PhD

Director, Urologic Oncology Disease Research Group

Associate Professor, Medicine

Leigh Ellis, PhD is the Scientific Director of the Urologic Oncology Program at Cedars-Sinai Cancer. His work within the lab focuses on genetic and epigenetic mechanisms behind prostate cancer. His lab utilizes in vitro genetically modified human and mouse cell lines and 3D organoid cultures as well as in vivo genetically engineered mouse models coupled with innovative technology including next generation sequencing approaches. The overall goal of his lab is to identify novel genomic and epigenomic mechanisms which will lead to the discovery of biomarkers and therapeutic targets for clinical testing, with a specific focus on tumor and immune cell lineage plasticity in prostate cancer driven by the loss; the tumor suppressor protein, retinoblastoma-1 (RB) and collaboration with the histone modifying enzyme enhancer of zeste homolog-2 (EZH2).

  • Doctorate: Australian National University, 2008
  • Post Doctorate: Johns Hopkins University, 2009
  • Post Doctorate: Roswell Park Cancer Institute, 2012

English

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