• IM/Allergy

One of the most important roles of the immune system is to recognize the presence of an infection or injury and to trigger an immunologic response aimed at restoring normal function of the organism. Specialized white blood cells from the innate immune system carry receptors that are specifically activated by invading organisms or markers of trauma. Suzanne Cassel, MD, and Fayyaz Sutterwala MD, PhD, run a joint lab that studies these receptors, how they are activated and how that translates into an effective and appropriate immune response to both infectious and sterile insults.

• Undergraduate: Reed College, 1992
• Medical School: Temple University, 2000
• Internship: Yale-New Haven Hospital, 2001
• Residency: Yale-New Haven Hospital, 2003
• Fellowship: Yale University School of Medicine, 2007

• Asthma
• Lung Institute (Women's Guild Lung Institute)
• Infectious Disease

Click here for a list of peer-reviewed publications.

• Ciraci C, Janczy, Jain N, Haasken S, Pecli E Silva C, Benjamim CF, Sadler JJ, Olivier AK, Iwakura Y, Shayakhmetov DM, Sutterwala FS, Cassel SL. 2016. Immune Complexes Indirectly Suppress the Generation of Th17 Responses In Vivo. PLoS One. 11:e0151252.
• Sutterwala FS, Haasken S, Cassel SL. 2014. Mechanism of NLRP3 inflammasome activation. Ann NY Acad Sci. 1319:82-95. PMC4074217
• Cassel SL*, Janczy JR, Bing X, Wilson SP, Olivier AK, Otero JE, Iwakura Y, Shayakhmetov DM, Bassuk AG, Abu-Amer Y, Brogden KA, Burns TL, Sutterwala FS*, Ferguson PJ*. 2014. Inflammasome-independent IL-1β mediates autoinflammatory disease in Pstpip2-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 111:1072-1077. PMC3903222 * equal contribution