• Neurosurgery

The research of Keith L Black, MD, focuses on biology of blood-brain barrier (BBB) and biochemical modulation of the blood-brain tumor barrier (BTB), targeted drug delivery, tumor immunology, cancer vaccines, cancer stem cells, microwave tumor ablation, nanotechnology for drug delivery, optical guided surgery for brain tumors, and Alzheimer's retinal imaging.

View NIH Biographical Sketch as a PDF

• Medical School: University of Michigan School of Medicine, 1981
• Internship: University of Michigan School of Medicine, 1982
• Residency: University of Michigan School of Medicine, 1987

View CV as a PDF

• Cancer Institute (Samuel Oschin Comprehensive Cancer Institute)
• Brain Tumor Center (Johnnie L. Cochran, Jr. Brain Tumor Center)
• Department of Neurology and Neurosurgery
• Cancer
• Neurosurgery

• Editorial Board: Public Library of Science (PLoS), Current
• Cedars-Sinai Pioneer in Medicine Award, 2018
• Whitney M. Young, Jr. Living Legend Award, National Urban League, 2011
• America's Top Doctors and Best Doctors in America, 2007, Current
• Jacobs Javitz Award, NIH National Institute of Neurological Disorders and Stroke, 2000

Click here for a list of peer-reviewed publications.

• Sun T, Patil R, Galstyan A, Klymyshyn D, Ding H, Chesnokova A, Cavenee W, Furnari F, Ljubimov V, Shatalova E, Wagner S, Li D, Mamelak AN, Bannykh S, Patil CG, Rudnick J, Hu J, Grodzinski Z, Rekechenetskiy A, Falahatian V, Lyubimov A, Leoh LS, Chen YM, Daniels-Wells T, Penichet P, Holler E, Ljubimov A, Black KL, Ljubimova JY. Blockade of a laminin-411 - Notch axis with CRISPR/Cas9 or a nanobioconjugate inhibits glioblastoma growth through tumor-microenvironment crosstalk. Cancer Res 2019 Jan 18. pii: canres.2725.2018. doi: 10.1158/0008-5472.CAN-18-2725.
• Kittle D, Vasefi F, Patil CG, Mamelak AN, Black KL, Butte PV. Real time optical Biopsy: Time-resolved Fluorescence Spectroscopy instrumentation and validation. Scientific Reports. 2016 Dec 8;6:38190. doi: 10.1038/srep38190
• Chou S, Gangalum PR, Patil P, Cavenee WK, Furnari F, Galstyan A, DingH, Chesnokova A, Mashouf A, Fox I, Black KL, Holler E, Ljubimov AV, Ljubimova. JY. Simultaneous blockade of CK2 and EGFR pathways by tumor-targeted nanobioconjugates significantly improves therapeutic efficacy against glioblastoma multiforme. J Control Release. 244 (2016) 14-23. doi: 10.1016/j.jconrel.2016.11.001.